Thursday, March 21, 2019

The Death of Cancer: After Fifty Years on the Front Lines of Medicine, a Pioneering Oncologist Reveals Why the War on Cancer Is Winnable--and How We Can Get There - Vincent T. DeVita Jr. & Elizabeth DeVita-Raeburn

This book is shocking and frustrating and hopeful and fascinating. I recommend it to people who could get cancer, literally everyone. I don't think I can state how important this book is!  It's essentially a history of cancer treatment, quite literally.  When the author (now in his 80's) began his work in the 60's, there was some surgery and radiation, but mostly the "treatment" for cancer was a pat on the back and they sent you home to die. Seriously.  They didn't even TRY to do anything most of the time because "why? it will just prolong the suffering".   At one point, the author resigned from a lead position at a cancer hospital because no one would listen to him (never mind the fact that he'd  practically built the NCI and Sloak-Kettering himself). The announcement was done by his primary antagonist who explained that "the problem with Dr. DeVita is that he wants to cure cancer."

There were and continue to be so many problems, it's a miracle anyone goes into remission! Here are a pair of examples:

1) The author begins the book with a story about his friend, Lee, who develops prostate cancer at the age of 60.  The author makes recommendations to doctor after doctor, pulling a few strings to get Lee the best care. It works.  At diagnosis, Lee was given a very grim outlook, he had all the worst signs.  But using Dr. DeVita's vast knowledge and connections they push Lee's cancer into remission several times, but each time it comes back worse than before, and subsequently resistant to whatever treatment worked previously, but there were several steps in the process where he could have been cured and only red tape and bureaucratic bullshit stopped him.  The author got his friend enrolled in an experimental drug research group that had a good likelihood of working, but Lee's cancer was more dire than the subjects selected for the experiment, but because of his connections, Dr. DeVita was able to get Lee in a sort of tester side project: given the experimental drug alongside the subjects, but just not reported in the final paper because he didn't qualify for the study group.  The drugs works, but because Lee's cancer was larger, he needed to be on the drugs for longer.  He wasn't permitted. Why? Because the study ended. No actual reason.  Lee's cancer came back. Later research on more advanced stages determined that he would have been cured had he continued the regiment.  Then Dr. DeVita heard about another drug that was successful in advanced prostate cancers just like Lee's, but the research was completed.  The new research was testing the drug on less advanced stages.  It had not yet been approved by the FDA, which purposefully approves drugs slowly, even after they've been proved effective in people, so Lee wasn't allowed to have it even though it had been proven effective for his kind of cancer.  Lee lived much longer than his first doctor estimated, but in the end, he died for no reason other than the drug that would have saved his life was being sat on by the FDA.  The experiments were cut short and the drug fast-tracked because it was so successful.  It reached the market 2 years after Lee died.

2) The author was asked to weigh in on a rich Italian's son's cancer problem.  The type of cancer the son had was curable so Dr. DeVita was concerned when the Italian doctors were adamant that it wasn't working.  He flew all the way to Italy to figure out why.  He looked at the son's charts for 5 minutes and knew why.  The Italian doctors weren't giving the son full doses, they were afraid of causing too much discomfort and looking bad in front of the influential father.  All they'd done was teach the son's cells how to get around the medication.  The author sat down with the Italian doctors and told them what they were doing wrong, why and the consequences of it.  He meticulously laid out the doses and schedule they should be using.  They rolled their eyes at him, so he went to the father.  He informed the father what was wrong and why.  There was the Italian version of a national cancer hospital where Dr. DeVita knew the head physician and knew that the proper schedule would be followed, but the father refused to send his son there because it was "for poor people". The son died.  He died because of his father's pride and his doctors' fear.  Incidentally, don't be rich and famous and get cancer, their outcomes are always worse because the doctors do dumb shit they wouldn't otherwise do.

Even when the author himself got cancer, he had to fight tooth and nail to get the care he knew he needed.  And he chose not to go to the hospital that he currently worked at! Different places do better on different kinds of cancer.

We've gotten as far as we have because of one woman : Mary Lasker.  She, single-handedly, was the force behind getting federal funding to fight cancer. She CREATED The War on Cancer.  If you have a loved one, or if you yourself have survived cancer, you probably have this woman to thank.  Without her, we would be much, much farther behind than we currently are.

When it comes down to it, we have the tools to kill all but the most obscure or aggressive cancer, we just don't always use them properly for many different reasons: doctor's pride or ignorance, crappy leaders of a hospital, a lethargic FDA, and, most disturbingly, insurance companies (because it wouldn't be worth it.)  During my short 1.5 months at MD Anderson Cancer Center I've not interacted with doctors and the most of the patients I ever see are tiny pieces in tubes, but I already know of one person killed by an insurance company in our trials alone. Everyone else in the trial went into remission and were doing very well, but that one person's insurance decided to reject the payment. That is unacceptable. This kind of bullshit is becoming more common.  American needs to get her head out of her ass and remember that a person is worth more than a few dollars.  The current for-profit system is vile and people will continue to die unnecessarily until we destroy our current system.  This book will piss you off.  Again, I highly recommend it to everyone.

Sunday, March 10, 2019

Non-Campus Mentis: World History according to College Students - Anders Henriksson

This is a great book, though I think it might only be funny if you have a solid handle on both world history and geography.  I thought it was great.  It was compiled by a history professor of all the wack stuff he's read over the years in essay, term papers, and blue book exams.  Honestly, I can't imagine how much more there's been that just didn't make it into the book. This is great for a chuckle, and to feel wildly superior.
Sample:  The Black Plague - A plague of boobs

Monday, March 4, 2019

Cinder - Marissa Meyer

Another random selection, much better results than last time!
I would totally recommend this book to anyone who enjoys a fun fiction romp.  The premise is old-world fairy tales retold with a modern twist.  I really enjoyed the book and would absolutely read more by this author in the future!

Friday, February 22, 2019

Wishful Drinking - Carrie Fisher

Carrie Fisher has her photo in the mental diseases book. It's a still of her from when she was in Star Wars.  Her response, "See! I'm not crazy! That bitch is!" Ha hahaha!
This was a great book. It was essentially her stand-up routine, so it was fast and amusing, but also weird.  It would not have been any good if someone else had read it. I'm glad I got to listen to her talk about her own life.
It took me a bit to get used to her humor, but not long.  I love the heavy sarcasm.  I would strongly recommend this to anyone who loves a ridiculous, sarcastic, self-depreciating stand-up routine about the shitshow that is Hollywood!

Saturday, February 16, 2019

New York Burning: Liberty, Slavery, and Conspiracy in Eighteenth-Century Manhattan - Jill Lepore

This book is terrifying.  Terrifying in the same way the Salem witch trials were, which, to my great amusement, was a parallel someone made JUST after the concluding events of this book!

In 1741 there were a series of suspicious fires in New York City.  At this time, it was a large town of 10k people and made entirely of wood, so fire was a serious fear.  After a good number of fires (like 6 -10) were started, all within a few weeks of each other, the New Yorkers started pointing fingers. And what better group to blame than newly enslaved Africans? New York was had slavery at that time and a few years previous there had been significant loss of life from slave revolts in some of the locations these slaves came from in the caribbean.  So some slaves get blamed for starting fires, and while there's 0 proof one way or the other, I suspect a small few, maybe 2-4 men did actually start the fires.  However, if that's all it amounted to, there would have been no story.  As we've seen before, hysteria took hold, and suddenly all 2,000 slaves in the city were in on it!

In a nearly surreal coincidence (maybe not?), one young, powerless, maid girl began the finger pointing, just as in Salem.  She was incensed at having to serve food and ale to black men, or so she claimed, and told the court that there was a plot to burn the whole city hatched at this gathering.  Some slave men are jailed, then some more, then the white tavern keeper where the gathering was held along with his entire family, some more black people, and MORE black people.  Despite having no evidence of any actual arson, nearly everyone was killed for treason.  The lucky ones were hanged. This continued until they had killed nearly any slave who even MIGHT have been acquainted with any of the slaves who had been killed for treason and slave owners started to complain that they were having to watch their money burn at the stake.

The really terrifying part about this book is the monumentally dumbass logic employed by the courts in this era.  If you are guilty and confess, then we will hang you, or maybe pardon you, but if you maintain your innocence, then we will torture you, assume you're guilty, and burn you instead.  Unless, that is, you want to confess, then we won't burn you. And if your confession brings to light a new name, then you'll likely be pardoned.  SO DUMB!  I mean, I'd be surprised if people WEREN'T tripping over themselves to point fingers.

Sunday, February 3, 2019

Dr. Jekyll and Mr. Hyde - Robert Louis Stevenson

I've taken a liking to old school gothic horror, perhaps because of Anne Rice, perhaps just evolving taste.  I'm sure everyone knows the basic premise of this book, but it is absolutely worth reading fully to appreciate the literature.  I find that most of the time classic well-known books like this are much richer than the plays/movies/shows that recreate them, this one is no exception to that rule.
I would recommend this book to anyone who likes reading classics.

Saturday, February 2, 2019

A Beautiful, Terrible Thing - Jen Waite

This was a random pick recommended by my library's app: "If you liked this, you may also like this..." But nothing I've read was remotely like this, so I've no idea why it was recommended.
That being said, it was an interesting read, I'll give it that, but I certainly don't plan on reading anything similar ever again.  The book is about a woman's relationship that eventually crumbles and only afterwards does she finally recognize the signs of psychopathy in her husband.  It is both frightening and fascinating to watch this trainwreck of a relationship.  The author does a phenomenal job of detailing the obsessing many of us do when a relationship ends suddenly without it being slow, grating, or boring as I have seen in other relationship centered stories.  She also jumps back and forth in time very easily and clearly.  I've seen other authors unable to pull this off too.
Frankly, the only bad part of this story is the child. I hate children and do NOT want to continually hear about them.  Even the author writing about her cholicy child made me want to punch something! But, it was necessary because when the author began focusing on her child, she was no longer constantly stroking her husband's ego, jumpstarting the destruction of the relationship.  So it needed to be in there, and after she moved away from her husband, her child was pretty much her whole world, but ew.
Overall, I'd recommend this book to anyone who likes to watch relationship drama fiction as well as nonfiction unfolding on say facebook or so on.